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Meta-analysis
ACE Report #11952
Ace Report Cover Arthroplasty

Similar efficacy with EACA and TXA for reduction of blood loss in patients undergoing TKA


Study Type:Meta-analysis/Systematic Review
OE Level Evidence:2
Journal Level of Evidence:3

Epsilon-aminocaproic acid versus tranexamic acid in total knee arthroplasty: a meta-analysis study

J Orthop Traumatol. 2019 Jul 18;20(1):28.

Contributing Authors: O Riaz A Aqil S Asmar R Vanker J Hahnel C Brew R Grogan G Radcliffe

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Synopsis

3 studies (1691 patients) were included in this meta-analysis comparing EACA and TXA for the reduction of blood loss and transfusion requirement in total knee arthroplasty. The primary outcome of interest was blood loss and the amount of transfusion required. Secondary outcomes of interest included operative time, tourniquet time and complications. No significant differences were observed in all o...

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