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Assessing LIA efficacy with and without lipsomal bupivacaine addition in total knee arthroplasty

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Ace Report Cover
July 2019

Assessing LIA efficacy with and without lipsomal bupivacaine addition in total knee arthroplasty

Vol: 8| Issue: 7| Number:26| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

Local Infiltration Analgesia With Liposomal Bupivacaine Improves Early Outcomes After Total Knee Arthroplasty: 24-Hour Data From the PILLAR Study

J Arthroplasty. 2019 May;34(5):882-886.

Contributing Authors:
MA Mont JW Barrington SH Dysart DJ Del Gaizo N Sodhi

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Synopsis

139 adult patients scheduled for primary, unilateral total knee arthroplasty (TKA) were randomized to receive a local infiltration analgesia (LIA) of aqueous bupivacaine (HCl) with or without liposomal bupivacaine (LB). The outcomes of interest included the proportion of opioid-free patients in the first 24 hours, total opioid consumption, area under curve (AUC) of pain intensity on a Visual Analo...

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