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ACE Report #11838
Ace Report Cover Arthroplasty

COA/ICORS2019: Perioperative IA-IV TXA most effective regimen for reducing blood loss in TKA

Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Combined Intra-articular and Intravenous Tranexamic Acid Administration Associated with Improved Early Rehabilitation Outcomes after Total Knee Arthroplasty : A Randomised Controlled Trial

Contributing Authors: KY Chiu CH Yan PK Chan

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


179 patients scheduled for total knee arthroplasty were randomized to one of three tranexamic acid (TXA) administration groups: one group received intraarticular TXA combined with pre- and postoperative intravenous (IV) TXA; one group received intraarticular TXA combined with just preoperative IV TXA; and one group received intraarticular TXA alone. Significant differences between groups in favour...

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