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RCT
ACE Report #11694
Ace Report Cover Spine

No increase in adverse events with liposomal bupivacaine vs placebo in elective lumbar spine surgery


Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

Can Liposomal Bupivacaine Be Safely Utilized in Elective Spine Surgery?

Global Spine J. 2019 Apr; 9(2): 133–137.

Contributing Authors: L Brown E Koh M Shasti T Weir S Koenig I Yousaf O Yousaf O Tannous K Banagan D Gelb S Ludwig

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Synopsis

59 patients with degenerative spondylosis scheduled for elective open posterior lumbar decompression and instrumented fusion were randomized to receive a pre-wound closure injection of liposomal bupivacaine (266mg) or placebo for the treatment of post-operative pain. The primary outcome of interest was the incidence of adverse events. The secondary outcome of interest was the length of hospital st...

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