
Topical TXA superior to placebo in reducing blood loss after instrumented posterior spinal fusion

Topical TXA superior to placebo in reducing blood loss after instrumented posterior spinal fusion
A Randomized Controlled Trial of Topical Application of Tranexamic Acid in Patients with Thoracolumbar Spine Trauma Undergoing Long-Segment Instrumented Posterior Spinal Fusion
Asian Spine J. 2019 Feb;13(1):146-154.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
60 patients between the ages of 18-70 with thoracolumbar spinal injuries and scheduled for long segment instrumented posterior spinal fusion surgeries with local autologous bone grafts were randomized to receive topical tranexamic acid (TXA) or a placebo solution for the control of blood loss and need for transfusion. The primary outcome of interest was post-operative packed red blood cell transfu...
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