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RCT
ACE Report #11612
Ace Report Cover Spine

Topical TXA superior to placebo in reducing blood loss after instrumented posterior spinal fusion


Study Type:Randomized Trial
OE Level Evidence:1
Journal Level of Evidence:N/A

A Randomized Controlled Trial of Topical Application of Tranexamic Acid in Patients with Thoracolumbar Spine Trauma Undergoing Long-Segment Instrumented Posterior Spinal Fusion

Asian Spine J. 2019 Feb;13(1):146-154.

Contributing Authors: W Sudprasert T Tanaviriyachai K Choovongkomol S Jongkittanakul U Piyapromdee

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Synopsis

60 patients between the ages of 18-70 with thoracolumbar spinal injuries and scheduled for long segment instrumented posterior spinal fusion surgeries with local autologous bone grafts were randomized to receive topical tranexamic acid (TXA) or a placebo solution for the control of blood loss and need for transfusion. The primary outcome of interest was post-operative packed red blood cell transfu...

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