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Topical TXA superior to placebo in reducing blood loss after instrumented posterior spinal fusion
May 2019
Topical TXA superior to placebo in reducing blood loss after instrumented posterior spinal fusion
Study Type:Randomized Trial
OE Level Evidence:1
Journal Level of Evidence:N/A
A Randomized Controlled Trial of Topical Application of Tranexamic Acid in Patients with Thoracolumbar Spine Trauma Undergoing Long-Segment Instrumented Posterior Spinal Fusion
Asian Spine J. 2019 Feb;13(1):146-154.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
60 patients between the ages of 18-70 with thoracolumbar spinal injuries and scheduled for long segment instrumented posterior spinal fusion surgeries with local autologous bone grafts were randomized to receive topical tranexamic acid (TXA) or a placebo solution for the control of blood loss and need for transfusion. The primary outcome of interest was post-operative packed red blood cell transfu...
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