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ACE Report #11347
Ace Report Cover Arthroplasty

AAOS2019: PAI with liposomal bupivacaine does not reduce narcotic use vs. standard cocktail in TKA

Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Single Surgeon Head-to-Head Comparison of Liposomal Bupivacaine vs. a Cocktail of Peri-Articular Injection Medications used in Primary Total Knee Arthroplasty

Contributing Authors: CB Broome JR Schneider

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


189 patients scheduled for total knee arthroplasty were randomized to periarticular injection performed with either liposomal bupivacaine and marcaine, or marcaine, epinephrine, morphine, and toradol. Patients were assessed for narcotic consumption postoperatively. Results demonstrated no significant differences between groups in consumption of either oxycodone or tramadol. In addition, there was ...

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