Mannitol addition to HA improves early post-injection outcomes compared to HA alone for knee OA
Efficacy of a single intra-articular injection of 2% sodium hyaluronate plus 0.5% mannitol in patients with symptomatic osteoarthritis of the knee: A preliminary reportJ Med Assoc Thai. 2016 Oct;99(10):1094-101
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20 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were randomized to either a single intraarticular injection of combined sodium hyaluronate plus mannitol or no injection. Patients were assessed for outcome related to the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain, Stiffness, and Function scale, daily rescue diclofenac consumption, and adverse eve...
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