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RCT
ACE Report #10945
Ace Report Cover Osteoarthritis

Mannitol addition to HA improves early post-injection outcomes compared to HA alone for knee OA


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Efficacy of a single intra-articular injection of 2% sodium hyaluronate plus 0.5% mannitol in patients with symptomatic osteoarthritis of the knee: A preliminary report

J Med Assoc Thai. 2016 Oct;99(10):1094-101

Contributing Authors: P Lertwanich C Lamsam

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Synopsis

20 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were randomized to either a single intraarticular injection of combined sodium hyaluronate plus mannitol or no injection. Patients were assessed for outcome related to the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain, Stiffness, and Function scale, daily rescue diclofenac consumption, and adverse eve...

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