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Similar improvement in PROMs and serum CRP over 6 weeks between HA and N-Acetyl Cysteine for knee OA
April 2019
Similar improvement in PROMs and serum CRP over 6 weeks between HA and N-Acetyl Cysteine for knee OA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Comparison of Intra-articular Injection of Hyaluronic Acid and N-Acetyl Cysteine in the Treatment of Knee Osteoarthritis: A Pilot Study
Cartilage. 2017 Oct;8(4):384-390. doi: 10.1177/1947603516675915Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
20 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were randomized to a single intraarticular injection of either N-acetyl cysteine (NAC; 300mg/3mL) or hyaluronic acid (HA; 24mg/3mL). Patients were assessed for clinical scores, serum C-reactive protein level, and synovial fluid biomarkers before and 6 weeks after injection. Clinical results demonstrated no significant differences ...
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