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Assessing the efficacy of opioids in management of chronic, noncancer pain
December 2018
Assessing the efficacy of opioids in management of chronic, noncancer pain
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A
Opioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysis
JAMA. 2018;320(23):2448–2460. doi:10.1001/jama.2018.18472Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
OE EXCLUSIVE
Synopsis
96 randomized controlled trials were included in this meta-analysis and systematic review which sought to evaluate the efficacy and safety of opioid analgesia for chronic, noncancer pain compared to placebo and active comparator treatment. When compared to placebo, opioid therapy was associated with statistically significant effects with respect to pain relief, increase in physical function, and i...
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