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RCT
ACE Report #10858
Ace Report Cover Osteoarthritis

Comparing clinical scores and secondary surgery rate between MSC injection vs TKA for secondary OA


Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

Subchondral stem cell therapy versus contralateral total knee arthroplasty for osteoarthritis following secondary osteonecrosis of the knee

Int Orthop. 2018 Nov;42(11):2563-2571. doi: 10.1007/s00264-018-3916-9

Contributing Authors: P Hernigou JC Auregan CH Flouzat Lachaniette A Dubory N Chevallier H Rouard

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Synopsis

60 patients with bilateral secondary knee osteoarthritis to corticosteroid-induced osteonecrosis were randomized to have one knee treated with subchondral injection of mesenchymal stem cells, and one knee treated with total knee arthroplasty. Patients were assessed over a minimum of 8 years after treatment. Results demonstrated no significant difference between groups in outcome on the Knee Societ...

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