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Comparison of efficacy between Artz and Durolane HAs at 18 and 26 weeks in treatment of knee OA
July 2019
Comparison of efficacy between Artz and Durolane HAs at 18 and 26 weeks in treatment of knee OA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Comparison of two hyaluronic acid formulations for safety and efficacy (CHASE) study in knee osteoarthritis: a multicenter, randomized, double-blind, 26-week non-inferiority trial comparing Durolane to Artz
Arthritis Res Ther. 2015 Mar 10;17:51. doi: 10.1186/s13075-015-0557-xDid you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
349 patients with knee osteoarthritis were randomized to either one intraarticular injection of Durolane hyaluronic acid followed by four weekly subcutaneous sham injections, or five weekly intraarticular injections of Artz hyaluronic acid. Patients were assessed for primarily for response on the Western Ontario and McMaster Universities Osteoarthritis Index to determine if Durolane was noninferio...
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