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High- and low-dose BM-MSC injection versus control for treatment of knee osteoarthritis
June 2019
High- and low-dose BM-MSC injection versus control for treatment of knee osteoarthritis
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II)
J Transl Med. 2016 Aug 26;14(1):246. doi: 10.1186/s12967-016-0998-2Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
32 patients with Kellgren-Lawrence grade II-IV knee osteoarthritis were randomized to one of three injection groups: high-dose autologous bone marrow-derived mesenchymal stem cell injection and hyaluronic acid injection (high-dose MSC group), low-dose autologous bone marrow-derived mesenchymal stem cell injection and hyaluronic acid injection (low-dose MSC group), or hyaluronic acid injection alon...
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