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Similar fusion success rate between i-Factor allograft and local autograft in single-level ACDF

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Ace Report Cover
February 2019

Similar fusion success rate between i-Factor allograft and local autograft in single-level ACDF

Vol: 8| Issue: 2| Number:113| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

i-Factor™ Bone Graft vs Autograft in Anterior Cervical Discectomy and Fusion: 2-Year Follow-up of the Randomized Single-Blinded Food and Drug Administration Investigational Device Exemption Study

Neurosurgery. 2018 Sep 1;83(3):377-384. doi: 10.1093/neuros/nyx432

Contributing Authors:
RC Sasso AR Vaccaro MG Fehlings PM Arnold ME Janssen B Kopjar RF Heary

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Synopsis

319 patients with single-level cervical disc disease and scheduled for anterior cervical discectomy and fusion were randomized to the surgery completed with either an allograft (i-Factor™ Peptide Enhanced Bone Graft; Cerapedics Inc.) or local bone autograft. Patients were assessed over 1- and 2-year follow-up for rate of fusion success, a composite endpoint of overall success, clinical scores, and...

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