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ACE Report #10701
Ace Report Cover Foot & Ankle

Dehydrated human amnion/chorion membrane (dHACM) injection vs. placebo for plantar fasciitis

Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

Randomized Controlled Trial of Micronized Dehydrated Human Amnion/Chorion Membrane (dHACM) Injection Compared to Placebo for the Treatment of Plantar Fasciitis

Foot Ankle Int. 2018 Oct;39(10):1151-1161. doi: 10.1177/1071100718788549

Contributing Authors: S Cazzell J Stewart PS Agnew J Senatore J Walters D Murdoch A Reyzelman SD Miller

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147 patients with a diagnosis of plantar fasciities were randomized to injection therapy with either 40mg of micronized dehydrated human amnion/chorion membrane (dHACM) in 1mL saline or to placebo saline alone. In addition to injection, all patients were managed with orthoses for 2 weeks after injection. Patients were assessed primarily for change in visual analog pain score (VAS pain) from baseli...

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