Dronabinol effective in reducing neuropathic pain in multiple sclerosis after 48-week treatment

How to Cite

OrthoEvidence. Dronabinol effective in reducing neuropathic pain in multiple sclerosis after 48-week treatment. ACE Report. 2018;7(8):17. Available from: https://myorthoevidene.com/AceReport/Report/10576

Study Type:Therapy

OE Level Evidence:2

Journal Level of Evidence:N/A

Dronabinol is a safe long-term treatment option for neuropathic pain patients

Eur Neurol. 2017;78(5-6):320-329.

Contributing Authors: S Schimrigk M Marziniak C Neubauer EM Kugler G Werner D Abramov-Sommariva

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Synopsis

240 patients who had neuropathic pain that was associated with multiple sclerosis (MS) were randomly assigned to receive either dronabinol 7.5-15.0 mg daily for 16 weeks, or its respective placebo with the identical schedule. No significant differences in pain reduction and quality of life improvement were found in patients that received dronabinol compared to those that received placebo. In a fol...