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No difference with gabapentin versus placebo following rib fracture in critically ill patients

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Ace Report Cover
February 2019

No difference with gabapentin versus placebo following rib fracture in critically ill patients

Vol: 8| Issue: 2| Number:118| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

A double-blind, randomized controlled trial of gabapentin vs. placebo for acute pain management in critically ill patients with rib fractures

Injury. 2018 Sep;49(9):1693-1698. doi: 10.1016/j.injury.2018.06.002

Contributing Authors:
L Garabedian EE Moskowitz K Harden E Perkins-Pride M Asfaw C Preslaski KN Liasia R Lawless CC Burlew F Pieracci

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Synopsis

40 patients with one or more rib fractures were randomized to the addition of either gabapentin 300mg or placebo three times daily to a mutlimodal analgesia protocol. Patients were primarily assessed for analgesic outcomes over the first 7 days of treatment, including pain scores and narcotic consumption. Results on these measures demonstrated no significant differences between groups on any day. ...

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