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RCT
ACE Report #10542
Ace Report Cover Foot & Ankle

Postoperative zoledronic acid has no effect on healing after Lapidus arthrodesis and Akin osteotomy


Study Type:Randomized Trial
OE Level Evidence:1
Journal Level of Evidence:N/A

Early initiation of zoledronic acid does not impact bone healing or clinical outcomes of hallux valgus orthomorphia

J Int Med Res. 2018 Aug;46(8):3251-3261. doi: 10.1177/0300060518760128

Contributing Authors: L Yang M Yang

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Synopsis

120 postmenopausal women with osteoporosis and hallux valgus who were scheduled for combined Lapidus arthrodesis and Akin osteotomy were randomized to postoperative intervention an infusion of either 5mg zoledronic acid or placebo saline. Patients were followed-up for nonunion rates at the fusion and osteotomy sites, and clinical outcome on the Orthopedic Foot and Ankle Society (AOFAS) score. Nonu...

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