Comparing ketamine plus atropine vs ketamine alone for pediatric procedural sedation

Study Type:Meta-analysis/Systematic Review

OE Level Evidence:2

Journal Level of Evidence:N/A

Ketamine versus ketamine pluses atropine for pediatric sedation: A meta-analysis

Am J Emerg Med. 2018 Jul;36(7):1280-1286. doi: 10.1016/j.ajem.2018.04.010

Contributing Authors: S Feng Y Liu H Ding Z Wei A Li H Shi J Shi C Xing D Pan G Ning

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Synopsis

5 studies were included in this meta-analysis which compared the rates of various measures, including vomiting, nausea, desaturation, hypersalivation, rash, tachycardia, agitation and muscle laryngospasm, between ketamine plus atropine and ketamine alone for pediatric procedural sedation. The incidence of hypersalivation was significantly lower among the ketamine plus atropine groups, while incide...