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No significant effect of fibrin sealant on postoperative function following total knee arthroplasty

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Ace Report Cover
August 2018

No significant effect of fibrin sealant on postoperative function following total knee arthroplasty

Vol: 7| Issue: 8| Number:15| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

The effect of a fibrin sealant on knee function after total knee replacement surgery. Results from the FIRST trial. A multicenter randomized controlled trial

PLoS One. 2018 Jul 25;13(7):e0200804. doi: 10.1371/journal.pone.0200804

Contributing Authors:
WC Verra JA Van Hilten EW van Zwet RGHH Nelissen Á Honohan JG van der Bom

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Synopsis

498 patients scheduled for total knee arthroplasty were randomized to either intraoperative fibrin sealant application or to no additional fibrin sealant. Patients were assessed for the primary outcome of change in knee extension angle after 2 weeks. Among secondary outcomes included the change in knee flexion angle, length of hospital stay, and incidence of complications. Results demonstrated no ...

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