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Bone mineral density loss following total joint arthroplasty mitigated by bisphosphonate therapy
February 2019
Bone mineral density loss following total joint arthroplasty mitigated by bisphosphonate therapy
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A
Bisphosphonates for the preservation of periprosthetic bone mineral density after total joint arthroplasty: a meta-analysis of 25 randomized controlled trials
Osteoporos Int. 2018 Jul;29(7):1525-1537. doi: 10.1007/s00198-018-4488-7Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
25 randomized controlled trials were included in this meta-analysis which compared bisphosphonate therapy to control intervention for effect on postoperative bone mineral density following total hip and total knee arthroplasty. Overall, in THA and TKA cohorts, bisphosphonate therapy was associated with significantly greater total periprosthetic bone mineral density compared to control intervention...
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