Gabapentinoids, topiramate do not demonstrate significant effect on pain and disability in LBP
Anticonvulsants in the treatment of low back pain and lumbar radicular pain: a systematic review and meta-analysisCMAJ. 2018 Jul 3;190(26):E786-E793. doi: 10.1503/cmaj.171333
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Nine randomized controlled trials were included in the meta-analysis and systematic review, which was conducted to analyze the effects of anticonvulsants - including gabapentinoids and topiramate - in patients with either nonspecific low back pain or lumbar radicular pain secondary to spinal stenosis. Results on gabapentinoids demonstrated no significant differences relative to placebo on either p...
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