
Gabapentinoids, topiramate do not demonstrate significant effect on pain and disability in LBP

Gabapentinoids, topiramate do not demonstrate significant effect on pain and disability in LBP
Anticonvulsants in the treatment of low back pain and lumbar radicular pain: a systematic review and meta-analysis
CMAJ. 2018 Jul 3;190(26):E786-E793. doi: 10.1503/cmaj.171333Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Nine randomized controlled trials were included in the meta-analysis and systematic review, which was conducted to analyze the effects of anticonvulsants - including gabapentinoids and topiramate - in patients with either nonspecific low back pain or lumbar radicular pain secondary to spinal stenosis. Results on gabapentinoids demonstrated no significant differences relative to placebo on either p...
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