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Increasing dronabinol over 3 weeks does not improve cervical dystonia compared to placebo
September 2018
Increasing dronabinol over 3 weeks does not improve cervical dystonia compared to placebo
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Cannabinoid, CB1 agonists in cervical dystonia: Failure in a phase IIa randomized controlled trial
Basal Ganglia. 2011 ;1(2):91-95. http://dx.doi.org/10.1016/j.baga.2011.04.002Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
9 patients with cervical dystonia received increasing doses of 2.5 mg dronabinol or placebo for 3 weeks in a randomized order. The purpose of this study was to determine if dronabinol improved Toronto Western Hospital Spasmodic Torticollis Rating Scale, global impression scale, or visual analog pain scale scores compared to placebo, while maintaining a similar rate of adverse events. Results indic...
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