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Volume:7 Issue:9 Number:6 ISSN#:2564-2537
RCT
ACE Report #10440
Ace Report Cover Cannabis

THC effective for muscle stiffness relief due to MS after 12 weeks of treatment compared to placebo


How to Cite

OrthoEvidence. THC effective for muscle stiffness relief due to MS after 12 weeks of treatment compared to placebo. ACE Report. 2018;7(9):6. Available from: https://myorthoevidence.com/AceReport/Report/10440

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Multiple sclerosis and extract of cannabis: results of the MUSEC trial

J Neurol Neurosurg Psychiatry. 2012 Nov;83(11):1125-32. doi: 10.1136/jnnp-2012-302468

Contributing Authors: JCS J. P. H. Zajicek D Barnes PG Mattison Musec Research Group

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Synopsis

279 patients diagnosed with multiple sclerosis (MS) and experiencing muscle stiffness were randomly assigned to receive either oral capsules of delta-9-tetrahydrocannabinol (maximum dose per day: 25mg) or placebo capsules for 12 weeks. Patients were assessed on the proportion reporting relief (0-3 on a 11-point Category Rating Scale) in muscle stiffness, muscle spasm, body pain, and sleep quality ...

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