Inhaled THC demonstrated dose-dependent pain reduction and modest side effect 4 hours post-treatment

How to Cite

OrthoEvidence. Inhaled THC demonstrated dose-dependent pain reduction and modest side effect 4 hours post-treatment. ACE Report. 2018;7(9):9. Available from: https://myorthoevidene.com/AceReport/Report/10439

Study Type:Therapy

OE Level Evidence:2

Journal Level of Evidence:N/A

Efficacy of Inhaled Cannabis on Painful Diabetic Neuropathy

J Pain. 2015 Jul;16(7):616-27. doi: 10.1016/j.jpain.2015.03.008

Contributing Authors: JH Atkinson B Gouaux A T. D. U. M. S. M. Wallace

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Synopsis

16 patients with pain due to diabetic peripheral neuropathy were randomly assigned to inhale either high dose, medium dose, low dose (7%, 4%, 1% by weight, respectively) of delta-9-tetrahydrocannabinol (THC), or placebo at the beginning each treatment session. The study consists of four 2-week treatment sessions, where participants received treatment at the beginning and used the remaining 2 weeks...