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ACE Report #10431
Ace Report Cover Arthroplasty

NSAIDs associated with reduction in heterotopic ossification development versus placebo in THA

Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A

Non-steroidal anti-inflammatory drugs for heterotopic ossification prophylaxis after total hip arthroplasty

Bone Joint J. 2018 Jul;100-B(7):915-922. doi: 10.1302/0301-620X.100B7.BJJ-2017-1467.R1

Contributing Authors: DF Amanatullah M Joice GI Vasileiadis

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29 randomized controlled trials were selected for inclusion in this meta-analysis which compared the rates of heterotopic ossification after total hip arthroplasty between groups of patients treated with selective non-steroidal anti-inflammatory drugs (NSAIDs), groups treated with non-selective NSAIDS, and groups treated with placebo. Compared to placebo, both selective and non-selective NSAID gro...

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