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Volume:9 Issue:8 Number:10 ISSN#:2564-2537
ACE Report #10386
Ace Report Cover Cannabis

Dronabinol increases pain threshold compared to placebo for functional chest pain over 4 weeks

How to Cite

OrthoEvidence. Dronabinol increases pain threshold compared to placebo for functional chest pain over 4 weeks. ACE Report. 2020;9(8):10. Available from: https://myorthoevidence.com/AceReport/Report/10386

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Dronabinol increases pain threshold in patients with functional chest pain: a pilot double-blind placebo-controlled trial

Dis Esophagus. 2017 Feb 1;30(2):1-8. doi: 10.1111/dote.12455

Contributing Authors: Z Malik L Bayman J Valestin A Rizvi-Toner S Hashmi R Schey

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Thirteen patients with non-cardiac functional chest pain were randomized to receive 5 mg capsules of dronabinol or placebo twice daily for 4 weeks. Patients described their chest pain episodes, completed the Short Form-36 (SF-36), Beck Anxiety Inventory and Beck Depression Inventory, and rated their pain during esophageal balloon distention tests (EBDT) to determine if dronabinol increased pain th...

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