Delta 9-THC has better analgesic effect compared to placebo for neuropathic pain over 8 hours

How to Cite

OrthoEvidence. Delta 9-THC has better analgesic effect compared to placebo for neuropathic pain over 8 hours. ACE Report. 2018;7(10):1. Available from: https://myorthoevidene.com/AceReport/Report/10385

Study Type:Randomized Trial

OE Level Evidence:1

Journal Level of Evidence:N/A

An Exploratory Human Laboratory Experiment Evaluating Vaporized Cannabis in the Treatment of Neuropathic Pain From Spinal Cord Injury and Disease

J Pain. 2016 Sep;17(9):982-1000. doi: 10.1016/j.jpain.2016.05.010

Contributing Authors: H Zhao B Wilsey R Deutsch TD Marcotte H Prasad A Phan

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Synopsis

42 patients with neuropathic pain related to spinal cord injury and disease took a placebo, 2.9%, and 6.7% delta 9-THC in a randomized order. The primary outcome was pain intensity, and patients were also assessed for allodynia, heat-pain threshold, response to painful stimuli, subjective psychoactive effects, spasticity, and vital signs. Patients also completed neuropsychological tests after taki...