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Tetrahydrocannabinol 8mg does not demonstrate better efficacy vs diazepam for chronic pancreatitis
September 2018
Tetrahydrocannabinol 8mg does not demonstrate better efficacy vs diazepam for chronic pancreatitis
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A
Single dose delta-9-tetrahydrocannabinol in chronic pancreatitis patients: Analgesic efficacy, pharmacokinetics and tolerability
Br J Clin Pharmacol. 2016 Mar;81(3):525-37. doi: 10.1111/bcp.12811Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
22 patients with chronic pancreatitis took 8 mg of delta-9-tetrahydrocannbinol (Δ9-THC) with placebo diazepam or placebo Δ9-THC with diazepam at 2 sessions in a randomly allocated sequence for this crossover trial. Blood samples were examined for the pharmacokinetic and pharmacodynamic properties of Δ9-THC, and reduction in pain was measured by the VAS scale. Bond and Lader visual analogue scales ...
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