Tetrahydrocannabinol 8mg does not demonstrate better efficacy vs diazepam for chronic pancreatitis
How to Cite
OrthoEvidence. Tetrahydrocannabinol 8mg does not demonstrate better efficacy vs diazepam for chronic pancreatitis. ACE Report. 2018;7(9):24. Available from: https://myorthoevidence.com/AceReport/Report/10383
Single dose delta-9-tetrahydrocannabinol in chronic pancreatitis patients: Analgesic efficacy, pharmacokinetics and tolerabilityBr J Clin Pharmacol. 2016 Mar;81(3):525-37. doi: 10.1111/bcp.12811
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22 patients with chronic pancreatitis took 8 mg of delta-9-tetrahydrocannbinol (Δ9-THC) with placebo diazepam or placebo Δ9-THC with diazepam at 2 sessions in a randomly allocated sequence for this crossover trial. Blood samples were examined for the pharmacokinetic and pharmacodynamic properties of Δ9-THC, and reduction in pain was measured by the VAS scale. Bond and Lader visual analogue scales ...
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