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Dronabinol improves chronic non-cancer pain when added to standard opioid therapy

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Ace Report Cover
October 2018

Dronabinol improves chronic non-cancer pain when added to standard opioid therapy

Vol: 7| Issue: 10| Number:2| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Efficacy of Dronabinol as an Adjuvant Treatment for Chronic Pain Patients on Opioid Therapy

J Pain. 2008 Mar;9(3):254-64

Contributing Authors:
SS Nedeljkovic S Narang AD Wasan D Gibson EL Ross E Michna RN Jamison

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Synopsis

30 chronic pain patients who were on stable doses of opioids received a single dose of each of10 mg of dronabinol (a synthetic cannabinoid), 20 mg dronabinol, or placebo in a random order, followed by 4 weeks of 5-60 mg dronabinol (open-label). The primary outcome was total pain relief at 8 hours in the randomized phase and change in pain intensity on a numeric rating scale (NRS) in the open-labe...

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