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Oral tetrahydrocannabinol (THC) does not reduce chronic abdominal pain compared to placebo
September 2018
Oral tetrahydrocannabinol (THC) does not reduce chronic abdominal pain compared to placebo
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Tetrahydrocannabinol Does Not Reduce Pain in Patients With Chronic Abdominal Pain in a Phase 2 Placebo-controlled Study
Clin Gastroenterol Hepatol. 2017 Jul;15(7):1079-1086.e4. doi: 10.1016/j.cgh.2016.09.147Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
65 patients with chronic abdominal pain following surgery or due to chronic pancreatitis were randomized to receive delta-9-tetrahydrocannabinol (THC) or placebo for 50-52 days. The primary outcome was pain relief, as measured by a visual analogue scale (VAS). Secondary outcomes included other measures of pain, depression, anxiety, quality of life, treatment satisfaction, appetite, alertness, mood...
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