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Dronabinol similar in safety and efficacy as diphenhydramine for neuropathic pain relief

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Ace Report Cover
October 2018

Dronabinol similar in safety and efficacy as diphenhydramine for neuropathic pain relief

Vol: 7| Issue: 10| Number:53| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Effect of dronabinol on central neuropathic pain after spinal cord injury: a pilot study

Am J Phys Med Rehabil. 2010 Oct;89(10):840-8. doi: 10.1097/PHM.0b013e3181f1c4ec

Contributing Authors:
DH Rintala RN Fiess G Tan SA Holmes BM Bruel

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Synopsis

9 patients with spinal cord injury and experiencing chronic neuropathic pain were randomly assigned to treatment with either dronabinol or diphenhydramine for 56 days, and then crossed over to the other medication for 56 days after a 7-day washout period. Patient-reported pain intensity and the incidence of side effects were assessed at the beginning and the end of each medication phase. The resul...

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