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Similar extended VTE prophylaxis efficacy and safety between rivaroxaban and aspirin following TJA
February 2019
Similar extended VTE prophylaxis efficacy and safety between rivaroxaban and aspirin following TJA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty
N Engl J Med. 2018 Feb 22;378(8):699-707Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
3427 patients who had undergone either total knee or hip arthroplasty with a 5-day course of rivaroxaban 10mg postoperatively were randomized to extended thromboprophylaxis with either aspirin 81mg daily or continued rivaroxaban 10mg daily. Patients were assessed for the incidence of venous thromboembolism, major bleeding events, and clinically relevant nonmajor bleeding events over the first 90 d...
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