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Transdermal buprenorphine offers analgesia similar to oral tramadol in post-spinal fusion management

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Ace Report Cover
January 2018

Transdermal buprenorphine offers analgesia similar to oral tramadol in post-spinal fusion management

Vol: 7| Issue: 1| Number:4| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Comparative study of the efficacy of transdermal buprenorphine patches and prolonged-release tramadol tablets for postoperative pain control after spinal fusion surgery: a prospective, randomized controlled non-inferiority trial

Eur Spine J. 2017 Nov;26(11):2961-2968

Contributing Authors:
HJ Kim CK Lee JS Yeom BS Chang HS Ahn Y Nam

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Synopsis

71 patients scheduled for single-level posterior lumbar interbody fusion were randomized to postoperative analgesia, beginning at 36 hours after surgery, with either transdermal buprenorphine patches or oral tramadol. Transdermal buprenorphine patch doses ranged from 5-20ug/hr and were replaced every 7 days, while oral tramadol doses ranged from 150-300mg daily. Patients were assessed for pain sco...

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