OE JOURNAL
OE Journal
Vol. 14 | Iss. 6 | March 2026 - 37 Studies
Questions This Issue Explores
This issue addresses surgical and perioperative management across orthopaedics, including operative techniques, implant strategies, intraoperative adjuncts, and perioperative pharmacologic prophylaxis and analgesia. It also covers rehabilitation and nonoperative therapeutic modalities, spanning physiotherapeutic programs, digital and home-based rehabilitation technologies, and biologic or adjunct injections and supplements for joint and soft-tissue conditions.
ORIGINAL ANALYSIS
From Miracle to Mystery: What No One Tells You About Peptide Therapy
Peptide therapy is rapidly gaining popularity as the latest “miracle” health trend, promising benefits ranging from faster injury recovery to improved skin, weight loss, and athletic performance. Short chains of amino acids that naturally occur in the body, peptides play important roles in hormone regulation and cellular signalling, yet many of the injectable forms promoted online remain unregulated and lack robust clinical evidence. Despite growing use of compounds such as BPC-157 and TB-500 in sports medicine and orthopaedics, most supporting evidence comes from small human studies or animal research, limiting confidence in their safety and effectiveness. Potential risks include allergic reactions, improper dosing, unknown drug interactions, and complications from self-injection. While early findings appear promising for tissue healing and inflammation, current evidence remains insufficient, highlighting the need for rigorous randomized trials before widespread clinical adoption.
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