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Musculoskeletal Evidence
Osteoarthritis
Collagen protein supplementation does not modulate biomarkers of bone metabolism following total hip arthroplasty: a randomized, double-blind, placebo-controlled trial.
Clin Nutr ESPEN. 2026 01-Jun;():. 10.1016/j.clnesp.2026.103253
Collagen protein supplementation does not modulate biomarkers of bone metabolism following total hip arthroplasty: a randomized, double-blind, placebo-controlled trial.
Clin Nutr ESPEN. 2026 01-Jun;():. 10.1016/j.clnesp.2026.103253
Osteoarthritis
Effects of orally administered cetylated fatty acids on symptoms and functional capacity in patients with knee osteoarthritis: results of a randomized, double-blind, placebo-controlled study.
Eur J Clin Nutr. 2025 01-Nov;():. 10.1038/s41430-025-01656-4
Effects of orally administered cetylated fatty acids on symptoms and functional capacity in patients with knee osteoarthritis: results of a randomized, double-blind, placebo-controlled study.
Eur J Clin Nutr. 2025 01-Nov;():. 10.1038/s41430-025-01656-4
Osteoarthritis
The effectiveness of dietary intervention in osteoarthritis management: a systematic review and meta-analysis of randomized clinical trials.
Eur J Clin Nutr. 2025 01-Oct;():. 10.1038/s41430-025-01622-0
The effectiveness of dietary intervention in osteoarthritis management: a systematic review and meta-analysis of randomized clinical trials.
Eur J Clin Nutr. 2025 01-Oct;():. 10.1038/s41430-025-01622-0
Osteoarthritis
Probiotics improve functional performance in patients with osteoarthritis: a randomized placebo-controlled clinical trial.
Eur J Nutr. 2025 01-Oct;():. 10.1007/s00394-025-03805-8
Probiotics improve functional performance in patients with osteoarthritis: a randomized placebo-controlled clinical trial.
Eur J Nutr. 2025 01-Oct;():. 10.1007/s00394-025-03805-8
Osteoarthritis
Saccharomyces boulardii improves clinical and paraclinical indices in overweight/obese knee osteoarthritis patients: a randomized triple-blind placebo-controlled trial.
Eur J Nutr. 2024 01-Sep;():. 10.1007/s00394-024-03428-5
Saccharomyces boulardii improves clinical and paraclinical indices in overweight/obese knee osteoarthritis patients: a randomized triple-blind placebo-controlled trial.
Eur J Nutr. 2024 01-Sep;():. 10.1007/s00394-024-03428-5
Trauma
Nutrition Supplementation Can Reduce the Risk of Complications and Loss of Muscle Mass After Trauma, But What SubGroups Benefit the Most?
Nutrition Supplementation Can Reduce the Risk of Complications and Loss of Muscle Mass After Trauma, But What SubGroups Benefit the Most?
Osteoarthritis
Probiotics' supplementation alleviates disease severity and improves postural balance by repairing intestinal leak in patients suffering from osteoarthritis: a double-blinded clinical trial.
Br J Nutr. 2024 01-Dec;():. 10.1017/S0007114524002824
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Probiotics' supplementation alleviates disease severity and improves postural balance by repairing intestinal leak in patients suffering from osteoarthritis: a double-blinded clinical trial.
Br J Nutr. 2024 01-Dec;():. 10.1017/S0007114524002824
General Orthopaedics
Improved physical disability and nutritional status by bovine colostrum supplementation in adults with traumatic peri-trochanteric femoral fracture: A randomized, controlled, clinical trial.
Injury. 2024 01-Mar;():. 10.1016/j.injury.2023.111253
Improved physical disability and nutritional status by bovine colostrum supplementation in adults with traumatic peri-trochanteric femoral fracture: A randomized, controlled, clinical trial.
Injury. 2024 01-Mar;():. 10.1016/j.injury.2023.111253
Osteoarthritis
Effect of high plant protein/peptide nutrition supplementation on knee osteoarthritis in older adults with sarcopenia: A randomized, double-blind, placebo-controlled trial.
Clin Nutr. 2024 01-Aug;():. 10.1016/j.clnu.2024.07.037
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Effect of high plant protein/peptide nutrition supplementation on knee osteoarthritis in older adults with sarcopenia: A randomized, double-blind, placebo-controlled trial.
Clin Nutr. 2024 01-Aug;():. 10.1016/j.clnu.2024.07.037
Arthroplasty
Associations of postoperative outcomes with geriatric nutritional risk index after conventional and robotic-assisted total knee arthroplasty: a randomized controlled trial.
Int J Surg. 2024 01-Apr;():. 10.1097/JS9.0000000000001048
Associations of postoperative outcomes with geriatric nutritional risk index after conventional and robotic-assisted total knee arthroplasty: a randomized controlled trial.
Int J Surg. 2024 01-Apr;():. 10.1097/JS9.0000000000001048
General Orthopaedics
Effectiveness of collagen supplementation on pain scores in healthy individuals with self-reported knee pain: a randomized controlled trial.
Appl Physiol Nutr Metab. 2020 01-Jul;():. 10.1139/apnm-2019-0654
Effectiveness of collagen supplementation on pain scores in healthy individuals with self-reported knee pain: a randomized controlled trial.
Appl Physiol Nutr Metab. 2020 01-Jul;():. 10.1139/apnm-2019-0654
Spine
Perceptually regulated training does not influence the differentiated RPE response following 16-weeks of aerobic exercise in adults with spinal cord injury.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 2020 ;():. 10.1139/apnm-2019-0062
Perceptually regulated training does not influence the differentiated RPE response following 16-weeks of aerobic exercise in adults with spinal cord injury.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 2020 ;():. 10.1139/apnm-2019-0062
Spine
Multimodal Nutritional Management in Primary Lumbar Spine Surgery: A Randomized Controlled Trial
Spine (Phila Pa 1976). 2019 Jul 15;44(14):967-974.
Multimodal Nutritional Management in Primary Lumbar Spine Surgery: A Randomized Controlled Trial
Spine (Phila Pa 1976). 2019 Jul 15;44(14):967-974.
Trauma
Cost-effectiveness of individualized nutrition and exercise therapy for rehabilitation following hip fracture
J Rehabil Med. 2016 Mar 29;48(4):378-85
Cost-effectiveness of individualized nutrition and exercise therapy for rehabilitation following hip fracture
J Rehabil Med. 2016 Mar 29;48(4):378-85
Arthroplasty
Multimodal perioperative care plus immunonutrition versus traditional care in total hip arthroplasty: a randomized pilot study
Nutr J. 2016 Apr 2;15:34.
Multimodal perioperative care plus immunonutrition versus traditional care in total hip arthroplasty: a randomized pilot study
This report has been verified by one or more authors of the original publication.
Nutr J. 2016 Apr 2;15:34.
Osteoarthritis
Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study
Nutr J. 2016 Jan 29;15(1):14
Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study
Nutr J. 2016 Jan 29;15(1):14
Metabolic Disorders
Effects of protein-rich nutritional supplementation and bisphosphonates on body composition, handgrip strength and health-related quality of life after hip fracture: a 12-month randomized controlled study
BMC Geriatr. 2015 Nov 17;15(1):149
Effects of protein-rich nutritional supplementation and bisphosphonates on body composition, handgrip strength and health-related quality of life after hip fracture: a 12-month randomized controlled study
BMC Geriatr. 2015 Nov 17;15(1):149
Trauma
Does Nutritional Intervention Improve Nutritional Outcomes in Orthopaedic Trauma Patients: A Randomized Prospective Study
Does Nutritional Intervention Improve Nutritional Outcomes in Orthopaedic Trauma Patients: A Randomized Prospective Study
Metabolic Disorders
Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial.
Am J Clin Nutr. 2014 Dec;100(6):1578-86.
Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial.
This report has been verified by one or more authors of the original publication.
Am J Clin Nutr. 2014 Dec;100(6):1578-86.
Trauma
Perioperative oral nutritional supplements in normally or mildly undernourished geriatric patients submitted to surgery for hip fracture: a randomized clinical trial
Clin Nutr. 2010 Oct;29(5):574-9
Perioperative oral nutritional supplements in normally or mildly undernourished geriatric patients submitted to surgery for hip fracture: a randomized clinical trial
Clin Nutr. 2010 Oct;29(5):574-9
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