Undenatured type II collagen supplementation for symptomatic management of knee OA .
Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study
Nutr J. 2016 Jan 29;15(1):14191 patients with knee osteoarthritis were randomized to oral supplementation with either undenatured type II collagen (UC-II), glucosamine hydrochloride plus chonndroitin sulfate (GC), or a placebo. The purpose of this study was to determine the efficacy of UC-II compared to GC or placebo in symptomatic management of mild-to-moderate knee osteoarthritis. Patient-reported outcome measures of the Western Ontario and McMaster Universities Osteoarthritis Index, a visual analog scale for pain, and the Lequesne Functional Index were assessed over 180 days of treatment. Results demonstrated significantly greater improvement from baseline to 180 days in all three outcome measures following treatment with UC-II versus either GC or placebo.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
