Platelet-Rich Plasma Versus Corticosteroid Injection in Patients With Primary Frozen Shoulder: A Single-Blinded Randomized Controlled Trial.

この研究はインパクトが大きい可能性があると判断されました。 OEのAIによるハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文の影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することができ、読者は将来の診療を形成する可能性が最も高い論文に焦点を当てることができます。

研究概要

90 patients with primary frozen shoulder in the freezing stage were included in this prospective, single-blinded controlled trial in which patients were randomized to either receive ultrasound-guided (USG) platelet-rich plasma (PRP) injection plus physical therapy, corticosteroid (CS) injection plus physical therapy, or normal saline (NS) injection plus physical therapy. Each participant received two USG injections into the glenohumeral joint and subacromial-subdeltoid bursa in addition to an 8-week standardized physical therapy program. The primary outcome of interest was the Shoulder Pain and Disability Index (SPADI). The secondary outcomes of interest were the Shoulder Disability Questionnaire (SDQ), visual analogue scale (VAS) for pain, active and passive range of motion (ROM), the 36-Item Short Form Health Survey (SF-36), and 5-point Likert scale for patient self-assessment. Outcomes were assessed at baseline (T0), 1 (T1), 2 (T2), 4 (T3), and 6 (T4) months after treatment initiation. Overall, the results of the study revealed that all three groups improved significantly following treatment. However, the CS group demonstrated greater reductions in pain and disability, greater improvements in range of motion and quality of life, and higher patient satisfaction than the PRP and NS groups. These findings suggest that corticosteroid injections combined with physical therapy are more effective than PRP during the freezing stage of primary frozen shoulder.