Platelet-Rich Plasma Versus Corticosteroid Injection in Patients With Primary Frozen Shoulder: A Single-Blinded Randomized Controlled Trial.

تم تحديد هذه الدراسة على أنها ذات تأثير كبير محتمل. يقدّر مقياس التأثير العالي الذي يعتمد على الذكاء الاصطناعي من OE التأثير المحتمل لورقة بحثية ما من خلال دمج إشارات من كل من المجلة التي نُشرت فيها والمحتوى العلمي للمقالة نفسها. تم تطوير نموذج OE High Impact باستخدام أحدث تقنيات معالجة اللغة الطبيعية، ويتنبأ نموذج OE High Impact بدقة أكبر بأداء الاقتباس المستقبلي للدراسة أكثر من معامل تأثير المجلة وحده. وهذا يتيح التعرف المبكر على الأبحاث ذات المغزى السريري ويساعد القراء على التركيز على المقالات التي من المرجح أن تشكل الممارسة المستقبلية.

ملخص الدراسة

90 patients with primary frozen shoulder in the freezing stage were included in this prospective, single-blinded controlled trial in which patients were randomized to either receive ultrasound-guided (USG) platelet-rich plasma (PRP) injection plus physical therapy, corticosteroid (CS) injection plus physical therapy, or normal saline (NS) injection plus physical therapy. Each participant received two USG injections into the glenohumeral joint and subacromial-subdeltoid bursa in addition to an 8-week standardized physical therapy program. The primary outcome of interest was the Shoulder Pain and Disability Index (SPADI). The secondary outcomes of interest were the Shoulder Disability Questionnaire (SDQ), visual analogue scale (VAS) for pain, active and passive range of motion (ROM), the 36-Item Short Form Health Survey (SF-36), and 5-point Likert scale for patient self-assessment. Outcomes were assessed at baseline (T0), 1 (T1), 2 (T2), 4 (T3), and 6 (T4) months after treatment initiation. Overall, the results of the study revealed that all three groups improved significantly following treatment. However, the CS group demonstrated greater reductions in pain and disability, greater improvements in range of motion and quality of life, and higher patient satisfaction than the PRP and NS groups. These findings suggest that corticosteroid injections combined with physical therapy are more effective than PRP during the freezing stage of primary frozen shoulder.