Platelet-Rich Plasma Versus Corticosteroid Injection in Patients With Primary Frozen Shoulder: A Single-Blinded Randomized Controlled Trial.

Diese Studie wurde als potentiell hochwirksam eingestuft. Die KI-gesteuerte High-Impact-Metrik von OE schätzt den Einfluss ein, den eine Arbeit wahrscheinlich haben wird, indem sie Signale sowohl der Zeitschrift, in der sie veröffentlicht wurde, als auch des wissenschaftlichen Inhalts des Artikels selbst integriert. Das mit Hilfe modernster natürlicher Sprachverarbeitung entwickelte OE High Impact-Modell sagt die zukünftige Zitationsleistung einer Studie genauer voraus als der Impact-Faktor einer Zeitschrift allein. Dies ermöglicht eine frühere Erkennung von klinisch bedeutsamer Forschung und hilft den Lesern, sich auf Artikel zu konzentrieren, die die zukünftige Praxis am ehesten beeinflussen werden.

Zusammenfassung der Studie

90 patients with primary frozen shoulder in the freezing stage were included in this prospective, single-blinded controlled trial in which patients were randomized to either receive ultrasound-guided (USG) platelet-rich plasma (PRP) injection plus physical therapy, corticosteroid (CS) injection plus physical therapy, or normal saline (NS) injection plus physical therapy. Each participant received two USG injections into the glenohumeral joint and subacromial-subdeltoid bursa in addition to an 8-week standardized physical therapy program. The primary outcome of interest was the Shoulder Pain and Disability Index (SPADI). The secondary outcomes of interest were the Shoulder Disability Questionnaire (SDQ), visual analogue scale (VAS) for pain, active and passive range of motion (ROM), the 36-Item Short Form Health Survey (SF-36), and 5-point Likert scale for patient self-assessment. Outcomes were assessed at baseline (T0), 1 (T1), 2 (T2), 4 (T3), and 6 (T4) months after treatment initiation. Overall, the results of the study revealed that all three groups improved significantly following treatment. However, the CS group demonstrated greater reductions in pain and disability, greater improvements in range of motion and quality of life, and higher patient satisfaction than the PRP and NS groups. These findings suggest that corticosteroid injections combined with physical therapy are more effective than PRP during the freezing stage of primary frozen shoulder.