Platelet-Rich Plasma Versus Corticosteroid Injection in Patients With Primary Frozen Shoulder: A Single-Blinded Randomized Controlled Trial.

Questo studio è stato identificato come potenzialmente ad alto impatto. La metrica High Impact di OE, guidata dall'AI, stima l'influenza che un articolo potrebbe avere integrando i segnali della rivista in cui è stato pubblicato e il contenuto scientifico dell'articolo stesso. Sviluppato utilizzando un'elaborazione del linguaggio naturale all'avanguardia, il modello High Impact di OE prevede in modo più accurato la futura performance citazionale di uno studio rispetto al solo fattore di impatto della rivista. Ciò consente di riconoscere prima le ricerche clinicamente significative e aiuta i lettori a concentrarsi sugli articoli che hanno maggiori probabilità di influenzare la pratica futura.

Riassunto dello studio

90 patients with primary frozen shoulder in the freezing stage were included in this prospective, single-blinded controlled trial in which patients were randomized to either receive ultrasound-guided (USG) platelet-rich plasma (PRP) injection plus physical therapy, corticosteroid (CS) injection plus physical therapy, or normal saline (NS) injection plus physical therapy. Each participant received two USG injections into the glenohumeral joint and subacromial-subdeltoid bursa in addition to an 8-week standardized physical therapy program. The primary outcome of interest was the Shoulder Pain and Disability Index (SPADI). The secondary outcomes of interest were the Shoulder Disability Questionnaire (SDQ), visual analogue scale (VAS) for pain, active and passive range of motion (ROM), the 36-Item Short Form Health Survey (SF-36), and 5-point Likert scale for patient self-assessment. Outcomes were assessed at baseline (T0), 1 (T1), 2 (T2), 4 (T3), and 6 (T4) months after treatment initiation. Overall, the results of the study revealed that all three groups improved significantly following treatment. However, the CS group demonstrated greater reductions in pain and disability, greater improvements in range of motion and quality of life, and higher patient satisfaction than the PRP and NS groups. These findings suggest that corticosteroid injections combined with physical therapy are more effective than PRP during the freezing stage of primary frozen shoulder.