ARTHROPLASTY
Similar outcome after retention or sacrifice of the posterior cruciate ligament in total knee arthroplasty
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original publication.
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2015;3(12):13 Acta Orthop. 2015 Apr;86(2):195-201.Posterior cruciate ligament (PCL) retention or sacrifice was compared in 20 studies. A total of 2347 knees from 1877 patients were considered. Statistically significant differences in postoperative flexion and KSS scores were observed in favor of sacrifice, however these differences did not reach clinical significance. Due to the lack of patient-important differences between these treatments neither can be recommended over the other.
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Was the bias in the selection of studies avoided?
Were the criteria used for assessing the validity of the included studies reported?
Was the validity of all of the studies referred to in the text assessed with use of appropriate criteria (either in selecting the studies for inclusion or in analyzing the studies that were cited)?
Were the methods used to combine the findings of the relevant studies (to reach a conclusion) reported?
Were the findings of the relevant studies combined appropriately relative to the primary question that the overview addresses?
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はい = 1
不確実＝0.5
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いいえ = 0
報告基準評価では、著者が出版物内で試験の方法論的特徴や試験特性を報告する際の透明性を評価します。評価は以下の5つのカテゴリーに分類されます。
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Introduction
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Accessing Data
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Analysing Data
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Results
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Discussion
Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65
Fragility Indexは、重要な所見の解釈を助けるツールで、結果の強さの尺度を提供します。Fragility Indexは、その所見が有意でなくなるために、二項対立の結果に追加する必要がある連続した事象の数を表します。数値が小さいほど弱い所見を表し、数値が大きいほど強い所見を表します。
なぜ今この研究が必要なのですか？
Retention of the posterior cruciate ligament (PCL) is a point of disagreement in total knee arthroplasty (TKA). The PCL has been found to provide normal proprioception and kinesthesia, as well as natural knee function. However, if the PCL is not balanced appropriately, many complications can arise. A previous meta-analysis was unable to determine if PCL retention or sacrifice provides better clinical outcomes. Since the publication of this meta-analysis a number of new trials have been completed. This meta-analysis will provide an update of previous work, giving an up to date view on the topic.
主な研究課題は何ですか？
Are there differences in functional, clinical, and radiological outcomes at a minimum of one year follow-up when comparing PCL-retaining and PCL-sacrificing total knee arthroplasty?
重要な知見は？
- 5 studies had low risk of bias, 5 studies had high risk of bias, and 10 studies had an unclear risk of bias
- There was a mean difference in postoperative flexion angle of 2.11 degrees (12 studies: [95% CI 0.23, 3.98]; p=0.03; I^2=29%)
- Knee Society functional score had a statistically significant increase of 2.36 points when PCL was sacrificed (9 studies: [95% CI 0.41, 4.3]; p=0.02; I^2=0.0%)
- WOMAC score had a non-significant difference between PCL sacrifice and retention (5 studies: [95% CI -0.35, 1.79]; p=0.19)
- No significant differences were found in the KSS pain, clinical or overall score, HSS score, SF-12, and radiolucent lines (p>0.05)
最も覚えておくべきことは？
There were no clinically relevant differences in clinical and functional outcomes between posterior cruciate ligament sacrifice and retention in TKA.
それが私の患者ケアにどのように影響するか？
No clinical difference was found between PCL sacrifice and retention in terms of functional and clinical scores. Results should be interpreted with caution, as many reports had either high risk of bias or an unclear risk of bias. Future studies should focus on additional outcomes, more preoperative information, cost effectiveness, and larger populations.
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