dGEMRIC able to detect change in knee OA cartilage after collagen hydrolysate treatment .
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Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolysate: a pilot randomized controlled trial
Osteoarthritis Cartilage. 2011 Apr;19(4):399-405. doi: 10.1016/j.joca.2011.01.001. Epub 2011 Jan 18Exclusive Author Interview
Dr. Flechsenhar discusses the use of collagen hydrolysate in the treatment of OA.
31 patients with knee osteoarthritis (OA) were randomized to receive collagen hydrolysate (CH) or a placebo to determine whether dGEMRIC or T2 mapping would be able to distinguish the changes in knee hyaline cartilage in these patients. Following assessments over a 48 week period, the results displayed that dGEMRIC was able to identify changes in cartilage status in the medial tibia and lateral tibia regions in patients who received CH. However, cartilage changes were not noticeable between the CH and placebo groups when using T2 mapping.
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