OrthoEvidence - Search

Arthroplasty
Efficacy of Tranexamic Acid in Reducing Blood Loss and Transfusion Requirements in Primary Total Knee Arthroplasty: A Prospective Comparative Study.
J Orthop Case Rep. 2026 01-Jun;():. 10.13107/jocr.2026.v16.i06.7382

Shoulder & Elbow
Tranexamic acid in arthroscopic repair of rotator cuff tears in the shoulder: a randomized trial.
Rev Assoc Med Bras (1992). 2026 01-Jun;():. 10.1590/1806-9282.20251543

Osteoarthritis

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Autologous platelet-rich plasma versus hyaluronic acid, corticosteroids or saline for knee osteoarthritis: can blood draw volume serve as a proxy for platelet dose? A systematic review and meta-analysis.
Int Orthop. 2026 01-May;():. 10.1007/s00264-026-06782-7

Physical Therapy & Rehab
The Efficacy of Tranexamic Acid in Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-Analysis.
Adv Orthop. 2026 01-Apr;():. 10.1155/aort/9180643

Osteoarthritis
PRP Plasma Gel vs Hyaluronic Acid vs Corticosteroid for Knee Osteoarthritis

Osteoarthritis

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Complications of Platelet-Rich Plasma Injection for Knee Osteoarthritis Are Similar to Those of Corticosteroids and Hyaluronic Acid but Are Significantly Greater Than Those of Placebo Injections: A Meta-analysis of Randomized Controlled Trials.
Arthroscopy. 2025 01-Nov;():. 10.1016/j.arthro.2025.05.018

Arthroplasty
Anti-inflammatory effect of multi-dose tranexamic acid in hip and knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials.
Inflammopharmacology. 2025 01-Mar;():. 10.1007/s10787-025-01679-0

Osteoarthritis

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Mesenchymal Stem Cells Injection Is More Effective Than Hyaluronic Acid Injection in the Treatment of Knee Osteoarthritis With Similar Safety: A Systematic Review and Meta-analysis.
Arthroscopy. 2025 01-Feb;():. 10.1016/j.arthro.2024.07.027

Osteoarthritis
Effects of orally administered cetylated fatty acids on symptoms and functional capacity in patients with knee osteoarthritis: results of a randomized, double-blind, placebo-controlled study.
Eur J Clin Nutr. 2025 01-Nov;():. 10.1038/s41430-025-01656-4

Shoulder & Elbow

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Tranexamic acid use in arthroscopic rotator cuff repair is an effective and safe adjunct to improve visualization: a systematic review and meta-analysis.
J Shoulder Elbow Surg. 2023 01-Nov;():. 10.1016/j.jse.2023.06.013

Peri-Operative
Equivalence of oral and intravenous tranexamic acid in knee arthroplasty: a systematic review and meta-analysis of randomized clinical trials.
Int J Surg. 2026 01-Jan;():. 10.1097/JS9.0000000000003347

Arthroplasty
Ascorbic Acid reduces the hidden blood loss after Total Hip Arthroplasty: Insights from a Randomized Controlled Trial

General Orthopaedics
What is the Best Method of Tranexamic Acid Administration in Extracapsular Hip Fractures? A Meta-analysis of Randomized Controlled Trials

Arthroplasty
No Effects of Extended Oral Tranexamic Acid following Total Knee Arthroplasty on Postoperative Pain and Range of Motion: A Randomized Controlled Trial

Peri-Operative

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Efficacy and Safety of Tranexamic Acid Combined with Absorbable Hemostat in Reducing Perioperative Blood Loss in Total Knee Arthroplasty: A Prospective, Blinded, Randomized Controlled Trial.
J Bone Joint Surg Am. 2025 01-Oct;():. 10.2106/JBJS.24.01236

General Orthopaedics

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Early Intra-articular Hyaluronic Acid Injection After Anterior Cruciate Ligament Reconstruction Provides Short-Term Pain Relief and Improves Early Postoperative Function With No Clinical Benefits at 6 and 12 Months: A Randomized Controlled Trial.
Arthroscopy. 2025 01-Sep;():. 10.1016/j.arthro.2025.02.010

Shoulder & Elbow
A therapeutic assessment of tranexamic acid on functional recovery after rotator cuff repair surgery: A study of early and mid-term follow-up.
J Orthop. 2025 01-Sep;():. 10.1016/j.jor.2025.02.006

Arthroplasty

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Intravenous Tranexamic Acid Does Not Improve Visual Field Clarity During Hip Arthroscopy: A Double-Blind, Randomized, Placebo-Controlled Trial.
Arthroscopy. 2025 01-Aug;():. 10.1016/j.arthro.2025.01.008

Shoulder & Elbow
Preoperative Intravenous Carbazochrome Sodium Sulfonate Improves Visual Clarity in Patients Undergoing Arthroscopic Rotator Cuff Repair Compared to Tranexamic Acid and Sodium Chloride: A Randomized Controlled, Triple-Blinded, Prospective Study.
Arthroscopy. 2025 01-Aug;():. 10.1016/j.arthro.2025.01.051

Trauma
Intramedullary administration of tranexamic acid reduces bleeding in proximal femoral nail antirotation surgery for intertrochanteric fractures in elderly individuals: A randomized controlled trial.
Chin J Traumatol. 2025 01-May;():. 10.1016/j.cjtee.2024.01.006