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The efficacy of tourniquet use in ankle trauma surgery
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TRAUMA
The efficacy of tourniquet use in ankle trauma surgery .

OrthoEvidence Journal (OE Journal) - ACE Report

OE Journal. 2014;2(7):33 Eur J Med Res. 2013 Dec 10;18:55. doi: 10.1186/2047-783X-18-55
Autores contribuintes

X Jiang B Yu W Qu J He

3 randomized controlled trials examining the safety and efficacy of tourniquet use in ankle trauma surgery were included in this meta-analysis. The purpose of this review was to compare operative time, hospital stay, ankle range of motion, postoperative infection rates and the incidence of deep venous thrombosis between patients undergoing surgery with or without the use of a tourniquet. Pooled results indicated that tourniquet use in ankle trauma surgery yielded a significantly longer hospital stay and reduced ankle range of motion. Operative time, postoperative infection rates, and the incidence of deep venous thrombosis were statistically similar between groups.


Detalhes do financiamento da publicação +
Financiamento:
Not Reported
Conflitos:
None disclosed

Risco de viés

9,5/10

Critérios de notificação

18/20

Índice de Fragilidade

N/A

Were the search methods used to find evidence (original research) on the primary question or questions stated?

Was the search for evidence reasonably comprehensive?

Were the criteria used for deciding which studies to include in the overview reported?

Was the bias in the selection of studies avoided?

Were the criteria used for assessing the validity of the included studies reported?

Was the validity of all of the studies referred to in the text assessed with use of appropriate criteria (either in selecting the studies for inclusion or in analyzing the studies that were cited)?

Were the methods used to combine the findings of the relevant studies (to reach a conclusion) reported?

Were the findings of the relevant studies combined appropriately relative to the primary question that the overview addresses?

Were the conclusions made by the author or authors supported by the data and or analysis reported in the overview?

How would you rate the scientific quality of this evidence?

Sim = 1

Incerto = 0,5

Não relevante = 0

Não = 0

A Avaliação dos Critérios de Relato avalia a transparência com que os autores relatam as caraterísticas metodológicas e do ensaio na publicação. A avaliação está dividida em cinco categorias que são apresentadas de seguida.

4/4

Introduction

4/4

Accessing Data

4/4

Analysing Data

3/4

Results

3/4

Discussion

Detsky AS, Naylor CD, O'Rourke K, McGeer AJ, L'Abbé KA. J Clin Epidemiol. 1992;45:255-65

O Índice de Fragilidade é uma ferramenta que auxilia na interpretação de achados significativos, fornecendo uma medida de força para um resultado. O Índice de Fragilidade representa o número de eventos consecutivos que precisam de ser adicionados a um resultado dicotómico para que o resultado deixe de ser significativo. Um número pequeno representa um resultado mais fraco e um número grande representa um resultado mais forte.

Porque é que este estudo era necessário agora?

Tourniquet use in orthopaedic surgery is thought to provide benefits such as improved visualization in the surgical field, shortened operative time, and minimized intraoperative blood loss. However, it may contribute to an increased risk in serious complications, such as pulmonary embolism, superficial wound infection, and acute thrombosis. Despite a number of meta-analyses having been conducted on this topic, the use of a tourniquet in orthopaedic surgery remains controversial. This meta-analysis summarized the results of randomized controlled trials evaluating the safety and efficacy of tourniquet use in ankle trauma surgery.

Qual era a principal questão de investigação?

Is the use of a tourniquet safe and effective in ankle trauma surgery?

Caraterísticas do estudo +
Fonte de dados:
PubMed, MEDLINE, EMBASE, and the Cochrane controlled trials register were searched for studies published prior to November 2012, via the literature tracing method. Google Scholar was used to retrieve the relevant studies.
Termos do índice:
The MeSH terms used for this search were: (randomized controlled trial or clinical trial) and tourniquet and ankle and surgery.
Seleção do estudo:
Inclusion criteria were: (1) primary research literature published at home and abroad, (2) randomized controlled trials or clinical controlled trials, (3) clear publication time, (4) clearly reported the sample size, (5) clearly reported diagnostic criteria, (6) surgical treatment used, (7) outcomes included operation time, hospital stays, postoperative joint range of motion, and complications, (8) scientific data collection method, (9) proper data analysis methods. Studies were excluded if they (1) did not provide the source of cases and control, or were non-therapeutic clinical studies or animal studies, (2) reported indeterminate diagnostic criteria, (3) had no control group, (4) did not undergo surgical treatment, (5) was characterized by an unscientific data collection method, (6) had wrong or no data analysis methods, (7) were reviews, (8) were duplicate studies, and (9) were retrospective studies.
Extração de dados:
Data extraction was performed independently by two reviewers. Extracted outcomes included postoperative infection rate, the incidence of deep venous thrombosis, hospital stay, and joint range of motion.
Síntese de dados:
Data was pooled using RevMan 5.0. Continuous outcomes were reported as mean differences (MD) and 95% confidence intervals (CI), and dichotomous outcomes were reported as relative risks (RR) and 95% CI. Heterogeneity was assessed via the I-squared test and by computing the Q-statistic. A random-effects model was used to pool data when studies were significantly heterogeneous (Q-statistic P<0.05), whereas a fixed-effects model was used if studies were statistically homogeneous.
Quais foram os resultados importantes?
  • 3 randomized controlled trials (n=166) were included in this meta-analysis. Between the three studies, 82 patients were in the tourniquet group and 84 patients were in the non-tourniquet group.
  • All 3 included studies reported data on operative time (n=166). Pooled data revealed no significant difference between tourniquet and no tourniquet (MD -5.45 [95% CI -13.98, 3.09]; p=0.21). This meta-analysis was performed using a random-effects model, as heterogeneity was found to be significant (p=0.02; I-squared=73%).
  • Pooled data from two studies (n=134) reporting hospital stay indicated that tourniquet use was significantly associated with a longer hospital stay (MD 3.17 [95% CI 1.39, 4.95]; p=0.0005). Heterogeneity was found to be insignificant (p=0.72; I-squared=0%).
  • Two studies (n=134) reported ankle range of motion. Via the fixed-effect model, pooled data found a significant difference in ankle range of motion, favouring the non-tourniquet group (MD -5.25 degrees [95% CI -9.61, -0.89]; p=0.02). Heterogeneity between studies was not statistically significant (p=0.51; I-squared=0%).
  • With respect to postoperative infection rates (2 studies; 134 patients), there was no significant difference with or without the use of a tourniquet (RR 1.83 [95% CI 0.65, 5.12]; p=0.25). Heterogeneity between studies was not significant for this outcome (p=0.88; I-squared=0%).
  • There was no significant difference in the incidence of deep venous thrombosis (2 studies; 134 patients) between the two groups (RR 4.13 [95% CI 0.47, 36.17]; p=0.20). Heterogeneity between studies was not significant for this outcome (p=0.84; I-squared=0%)
De que é que me devo lembrar mais?

Tourniquet use in ankle trauma surgery resulted in significantly longer hospital stay and reduced ankle range of motion. Operative time, postoperative infection rates, and the incidence of deep venous thrombosis were statistically similar between groups.

Como é que isto afectará o tratamento dos meus doentes?

Results from this meta-analysis suggest that, although safe, the use of a tourniquet in ankle trauma surgery may decrease range of motion and increase length of hospital stay. Additional randomized controlled trials are needed to confirm these findings. Furthermore, future meta-analyses should perform a funnel plot analysis to assess selection bias.

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OrthoEvidence. The efficacy of tourniquet use in ankle trauma surgery. OE Journal. 2014;2(7):33. Available from: https://myorthoevidence.com/AceReport/Show/the-efficacy-of-tourniquet-use-in-ankle-trauma-surgery

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