Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster-randomised trial in seven low-income and middle-income countries

この研究はインパクトが大きい可能性があると判断されました。 OEのAIによるハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文の影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することができ、読者は将来の診療を形成する可能性が最も高い論文に焦点を当てることができます。

研究概要

13,301 patients undergoing non-cesarean abdominal surgery were included in this cluster randomized trial in 7 low- and middle-income countries to assess whether the routine change of gloves and instruments before wound closure reduced the risk of surgical site infection. 7,157 were randomized to current/standard practice and 6,144 were randomized to the intervention group. The primary outcome of interest was surgical site infection within 30 days of surgery. Secondary outcomes of interest included mortality, surgical site infection at discharge, readmission, reoperation, return to normal activity, and length of hospital stay. The results revealed a robust benefit of routine glove/instrument change, which significantly lowered the risk of surgical site infection. No differences in secondary outcomes were observed.