2024 EFORT Annual Meeting: No significant differences in clinical outcome and survival between patient-specific instrumentation and conventional total knee arthroplasty: 10 year follow-up of a multicenter double blind randomized controlled trial

One hundred twenty-nine patients with knee osteoarthritis were randomized to receive either patient-specific instrumentation (PSI) (n=64) or conventional arthroplasty (CA) (n=65). The primary outcome of interest was patient-reported outcome measures (PROMs). Secondary outcomes of interest included revision rates and signs of loosening of the components on X-rays. Outcomes were assessed up to 10 years. Overall, the results of the study revealed no significant differences between PSI and CA in terms of PROMs and revision rates. This suggests that PSI does not offer a clinical advantage over CA, considering its higher costs.