The effects of repeated intra-articular PRP injections on clinical outcomes of early osteoarthritis of the knee

This report has been verified by one or more authors of the original publication.

この研究はハイインパクトの可能性があります。 OEのAI駆動型ハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文が持つ可能性の高い影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することが可能になり、読者は将来の診療を形成する可能性が最も高い論文に集中することができます。

93 patients with early-stage osteoarthritis (OA) of the knee were randomized to receive either a single cycle of platelet-rich plasma (PRP) treatment consisting of 3 injections, or to receive the same treatment plus an additional second cycle, repeated 1 year later. Patients were followed-up for a minimum of 2 years after initiation of treatment. The purpose of the study was to determine if annual repetition of the treatment resulted in pain reduction, improvement in quality of life or ability to participate in activities compared to a single course of injections. Results indicated a significant benefit to pain, activity level, and quality of life in the repeat injection group 18 months into treatment, although the differences were no longer significant at 24 months.