LSD modulates effective connectivity and neural adaptation mechanisms in an auditory oddball paradigm
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Vol. 10 Iss. 11 | June 2022 | Number 39
Neuropharmacology. 2018 23-Feb;():. 10.1016/j.neuropharm.2017.10.039
Study Summary
Twenty healthy subjects underwent a pseudo-randomized, placebo-controlled, magnetoencephalography (MEG) auditory oddball paradigm study to examine the effects of LSD on feedback and feedforward connections in perceptual learning and inference under the predictive coding framework. Subjects received LSD and placebo on different days. Scalp level Event Related Fields (ERF) showed reduced neural adaptation to familiar stimuli and an attenuated neural 'surprise' response to novel stimuli in the LSD condition. The presentation of both novel stimuli and LSD modulate backward extrinsic connectivity.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
Are you affiliated with one of our partner associations?
Click here to gain complimentary access as part your association member benefits!
0 of 4 monthly FREE articles unlocked
