76 patients undergoing arthroscopic rotator cuff repair (ARCR) for rotator cuff tears were randomized to receive a cervical plexus block and interscalene block (ISB; n=38) or general anesthesia (GA; n=38). Outcomes of interest included processing time, waiting time to surgery, operative time, morphine consumption, diclofenac use, time to rescue analgesia, patient and surgeon satisfaction, time to discharge, and pain on a Visual Analog Scale (VAS). VAS pain scores in PACU, and at 2 and 24 hours were significantly lower in the ISB group. Waiting time was significantly shorter in the GA group whereas morphine consumption, diclofenac consumption, patient and surgeon satisfaction, and discharge time were significantly better in the ISB group. Rescue analgesia was needed significantly earlier in the GA group.