Hypertonic Dextrose Injection for Patients with Chronic Supraspinatus Tendinosis .
Effect of Hypertonic Dextrose Injection on Pain and Shoulder Disability in Patients with Chronic Supraspinatus Tendinosis: A Randomized Double-Blind Controlled Study
Arch Phys Med Rehabil. 2022 Feb;103(2): 237-244.Fifty-seven patients with chronic supraspinatus tendinosis were randomized to receive an ultrasound-guided injection of hypertonic dextrose (n=29) or normal saline (n=28). The primary outcomes of interest included pain scores on a Visual Analog Scale (VAS) and function on the Shoulder Pain and Disability Index (SPADI). Secondary outcomes of interest included range of motion, supraspinatus thickness, and echogenicity. Outcomes were assessed up to 12 weeks follow-up. The dextrose group reported significantly lower pain, greater functional scores, and better range of motion in flexion vs. the control group at 2 weeks follow-up, however, these effects were not sustained to weeks 6 and 12.
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